Dopexamine hydrochloride
CAS No. 86484-91-5
Dopexamine hydrochloride( FPL60278AR )
Catalog No. M22574 CAS No. 86484-91-5
Dopexamine hydrochloride is a β2-adrenergic receptor agonist. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 102 | In Stock |
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10MG | 160 | In Stock |
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25MG | 335 | In Stock |
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50MG | 500 | In Stock |
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100MG | 705 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameDopexamine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionDopexamine hydrochloride is a β2-adrenergic receptor agonist. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects.
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DescriptionDopexamine hydrochloride is a β2-adrenergic receptor agonist. ?Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors.?Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow.(In Vitro):Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
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In VitroDopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. Dopexamine can attenuate the systemic inflammatory response, reduce tissue leukocyte infiltration, and protect against organ injury at doses that do not alter global hemodynamics or regional microvascular flow. Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine reduces the systemic inflammatory response to endotoxin, including cytokine release, endothelial adhesion molecules, and oxidative stress, without substantially changing systemic hemodynamics, either blood pressure or stroke volume.
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In Vivo——
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SynonymsFPL60278AR
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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Recptorβ2-adrenergic receptor
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Research AreaCancer
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IndicationOral Cancer|Head and Neck Cancer;Free Flap;Hypotension
Chemical Information
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CAS Number86484-91-5
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Formula Weight429.42
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Molecular FormulaC22H34Cl2N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (232.87 mM)
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SMILESCl.Cl.Oc1ccc(CCNCCCCCCNCCc2ccccc2)cc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bangash MN, et al. Dopexamine can attenuate the inflammatory response and protect against organ injury in the absence of significant effects on hemodynamics or regional microvascular flow. Crit Care. 2013 Mar 28;17(2):R57.
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